Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

Chouchani lab, Cell, November 2022

BAF complex maintains glioma stem cells in pediatric H3K27M-glioma

Filbin and Qi labs, Cancer Discovery, November 2022

Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response

Wu lab, Immunity, October 2022

MCL-1 is a master regulator of cancer dependency on fatty acid oxidation

Danial and Walensky labs, Cell Reports, October 2022

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

Ebert lab, Journal of Biological Chemistry, October 2022

Human differentiated eosinophils release IL-13 in response to IL-33 stimulation

Dougan lab, Frontiers in Immunology, September 2022

Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers

Agar lab, PLOS ONE, September 2022

Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

Losman lab, NPJ Precision Oncology, September 2022

Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors

Meyerson lab, Genome Medicine, August 2022

Untangling the web of intratumour heterogeneity

Polyak lab, Nature Cell Biology, August 2022

Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists

Kaelin lab, Science, August 2022

Three-phase DNA-origami stepper mechanism based on multi-leg interactions

Shih lab, Biophysical Journal, August 2022

October 2022

Congratulations to a CCBM Mentor, Kornelia Polyak, M.D., Ph.D. for her election to the prestigious National Academy of Medicine

Kornelia Polyak, M.D., Ph.D., professor of medicine, medical oncology, Dana-Farber Cancer Institute has been elected to the prestigious National Academy of Medicine. Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service. Read the full announcement here.

July 2022

Study Points to Link Between Genetic Ancestry and Genetic Signature of Lung Cancer

A study led by one of our mentors, Dr. Matthew Meyerson, discovered that genetic ancestry can influence molecular signatures of lung cancer. The analysis included lung cancer tissue from more than 1,100 patients in Mexico and Colombia, and was published in the March 2022 issue of Cancer Discovery. Read more here!

March 2022

Happy 75th Birthday Dana-Farber Cancer Institute!

Founded in 1947, Dana-Farber Cancer Institute, the home of our T32 Program, has been driving cancer care and transformative cancer research for 75 years now. The anniversary celebrations will continue throughout the year, and you can learn more about it here.

November 2021

Congratulations to our past trainees on their fellowships:

  • Narek Darabedia, PhD – National Cancer Center Fellowship
  • Laura Stevens, PhD – The Helen Gurley Brown Fellowship
  • Kedar Puvar, PhD – NIH Postdoctoral Fellowship (F32)

November 16, 2021

CCBM Mentors among world’s most highly cited researchers

Institute for Scientific Information at Clarivate has recently released their list of Highly Cited Researchers. The criteria for inclusion into this list is that a researcher needs to produce multiple papers ranking in the top 1% by citations for their field and year of publication.

We congratulate our mentors who have been included on this prestigious list: Myles Brown, MD; Benjamin Ebert, MD, PhD; Pasi Jänne, MD; Matthew Meyerson, MD, PhD; Margaret Shipp, MD; Bruce M. Spiegelman, PhD and Catherine J. Wu, MD.

Read the full press release here.

October 19, 2021

In Memoriam: David Morse Livingston, MD, Renowned Scientist and Esteemed Mentor

Dana-Farber community and many others in the field of cancer research were saddened by the unexpected death of David Morse Livingston, MD. Read more about Dr. Livingston’s impact on the field and his legacy here.

September 23, 2021

Congratulations to CCBM Mentor, Cigall Kadoch, Ph.D. for her selection as a Howard Hughes Medical Institute Investigator

Cigall Kadoch, Ph.D.

Cigall Kadoch, Ph.D. was named as a Howard Hughes Medical Institute (HHMI) Investigator. The HHMI Investigator Program is a prestigious and highly selective program that funds cutting-edge scientists as they pursue most pressing questions in biomedical research.

Read full announcement here!

July 09, 2021

Metabolomics Facility at Dana-Farber wins Massachusetts Life Sciences Center funding

Nika Danial, PhD

Congratulations to our co-director, Dr. Nika Danial for winning a $1.82 million grant from the Massachusetts Life Sciences Center to build a new cutting-edge metabolomics facility at Dana-Farber Cancer Institute. The Center will help accelerate basic and translational discoveries in the field of cancer and other disease, such as obesity, diabetes, neurologic disorders and inborn errors of metabolism. Read more about Dr. Danial’s plans for the new metabolomics facility here.

March 20, 2021

Bruce M. Spiegelman, PhD, receives 2021 Albert Renold Award, a major mentorship award

Bruce Spiegelman, Ph.D.

Congratulations to one of our mentors, Dr. Bruce Spiegelman for being named the recipient of the 2021 Albert Renold Award. This award is presented to an individual whose career is distinguished by outstanding achievements in the training and mentorship of diabetes research scientists and in the development of communities of scientists to enhance diabetes research. Read more about Dr. Spiegelman’s mentoring philosophy here.